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A community based molecular GPS for microbes to people

presented by

Pieter Dorrestein
University of Califonrnia - San Diego

April 17, 2014

TSRI Auditorium


Background:

The Dorrestein laboratory began at UCSD Sept. 1, 2006 and is a highly interdisciplinary environment. Dr. Dorrestein's lab uses chemical biological, organic chemical, biochemical, genomic, proteomic, bioanalytical, and other modern biomedical approaches to interrogate the classification of therapeutically relevant proteins that are related to the biosynthesis of secondary metabolites or involved in the formation of post-translational modifications. The Dorrestein lab has a FT-ICR mass spectrometer equipped with a nanospray robot to accomplish this research.

Two representative projects that are ongoing in the Dorrestein laboratory are: 1) The characterization of the virulence factor genes from group B streptococci. 2) Orphan polyketide and non-ribosomal peptide synthetase gene clusters.

Abstract:

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