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Multiple Ionization Strategy for Metabolomics

presented by

Anders Nordstrom
Scripps Center for Mass Spectrometry

February 15, 2007

W.M. Keck Foundation Amphitheater


Background:

     Anders received his PhD at the Swedish University of Agricultural Sciences (SLU) in Ume?, Sweden. His graduate work was focused on the interaction and analytical techniques of plant hormones. He is currently involved in metabolomics, proteomics and DIOS work.

Abstract:

     The multitude of metabolites present in human fluids or tissue represents a great challenge for comprehensive and non-targeted analysis. Ultrahigh pressure chromatography and multiple ionization strategies prior to mass spectrometry detection, enhances the metabolite coverage. This paired with an in-house developed nonlinear chromatogram alignment algorithm can provide a comprehensive analysis results in a format ready for further data mining.

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